FITC标记的电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体
产品名称： FITC标记的电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体
英文名称： Anti-SCN3A/FITC
产品编号： HZ-12133R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SCN3A/FITC Conjugated antibody
FITC标记的电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体
| 英文名称 | Anti-SCN3A/FITC |
| 中文名称 | FITC标记的电压门控钠通道SCN3α蛋白/Na+ CP type IIIα抗体 |
| 别 名 | NAC3; Sodium channel protein type 3 subunit alpha; Sodium channel protein type III subunit alpha; Sodium channel protein, brain III subunit alpha; Voltage gated sodium channel subtype III; Voltage gated sodium channel subunit alpha Nav1.3; SCN3A_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 通道蛋白 细胞膜受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 226kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SCN3A |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Function: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Subunit: The sodium channel consists of a large polypeptide and 2-3 smaller ones. This sequence represents a large polypeptide. Interacts with NEDD4L. Subcellular Location: Membrane; Multi-pass membrane protein. Post-translational modifications: May be ubiquitinated by NEDD4L; which would promote its endocytosis. Similarity: Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.3/SCN3A subfamily. Contains 1 IQ domain. Database links: Entrez Gene: 6328 Human Entrez Gene: 20269 Mouse Entrez Gene: 497770 Rat Omim: 182391 Human SwissProt: Q9NY46 Human SwissProt: P08104 Rat Unigene: 435274 Human Unigene: 330256 Mouse Unigene: 87394 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
电压门控钠通道是由具有24个跨膜结构域的大α亚基和一个或多个调节性β亚基组成的跨膜糖蛋白复合物。它们负责神经元和肌肉中动作电位的产生和传播。这个基因编码钠通道α亚单位基因家族的一个成员，并且在染色体2上的五个α亚单位基因簇中发现。该基因已发现编码不同亚型的多个转录变体。[ RefSeq，JUL 2008 ]提供。