Anti-TAP2 Polyclonal Antibody

品牌：solarbio | 货号：K002870P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002870P-50ul	solarbio	50ul	960.00元
K002870P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-TAP2 Polyclonal Antibody
别名	ABC18;ABCB3;APT2;D6S217E;PSF-2;PSF2;RING11
应用	WB IHC IF
稀释比例	WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	76kDa
Gene ID	6891
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human TAP2
性状	液体
Public Immunogen Range	Recombinant protein of human TAP2
Subcellular Locations	Endoplasmic reticulum membrane Multi-pass membrane protein
Swiss Prot	Q03519
克隆类型	Polyclonal Antibody
背景资料	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.